Inorwisa utachiona TSifran. Drug Usage

Medicine "TSifran" ane inorwisa utachiona mumiririri ane chakarondedzera chiito uye ndowenyika pharmacological boka fluoroquinolones. Active zvinoriumba zvinodhaka ndiko ciprofloxacin uye tinidazole. Nokuda kuti kudzvinyirira DNA gyrase uye kwemabhakitiriya DNA usage chinovhiringidza, izvi vanoshingaira zvinhu zviri zvikuru kushingaira vakawanda giremu negative tusingaoneki.

Kunyanya, basa bactericidal chiito rekugadzirira "TSifran" mirayiridzo Chinyorwa manotsi noruremekedzo kuti utachiona izvi: Neisseriagonorrhoeae, Neisseriameningitidis, Haemophilusinfluenzae, Pseudomonasaeruginosa, Salmonellaspp, Escherichiacoli uye mamwe majemusi utachiona kubudisa uye isingabereki penicillinase, uyewo methicillin nemishonga utachiona uye Enterococcusspp, Chlamydiaspp, Mycobacteriumspp, Legionellaspp ... utachiona.

Pharmacological kuitwa bactericidal medicament chakarondedzera "TSifran" mirayiridzo kushandiswa iri sezvinotevera: ". The chombo rinotarisirwa kuti kurapwa kwezvirwere zvakawanda zvinotapukira pathologies zvinobudirira pakurapa anogumbura pezvakaitwa - vakavhengana noutachiona kushatiriswa basa Kurovedza uye anaerobic zvigare uye majemusi".

Pharmacokinetics

The unorapa zvinodhaka "TSifran" mirayiridzo kushandiswa rinoreva zvikuru enderana. Uye ciprofloxacin uye tinidazole vane Absorção de Água yakanaka nemudumbu.

Kufunga nerimwe unorapa zvinodhaka, zvinofanira kucherechedzwa kuti ciprofloxacin ane vanenge 70% bioavailability. Absorção de Água Its ari kufambira zvishoma, apo kushandisa chikafu. mushonga uyu ane permeability yakanaka kupinda nzvimbo dzomuviri uye muviri zvinwiwa, kusanganisira pfupa, tsandanyama, mafuta, uye shwashwa tishu. Iye chinopinda mumba mapazi nezvezvimwe zvinetso zvedundira, kusanganisira mumuviri yakadai prostate. Raiva chakavanzika Rinozivisa refu wevasungwa kugutsikana kiprofloksatsina, sezvo, zvirokwazvo, uye mune urume, nemate, bile, node fluid madzihwa.

Tinidazole akasiyana Mhedziso bioavailability. chikamu ichi zvakare anowa nokukurumidza pane mukuru kuwanda mu zvinyama womunhu muviri emura svikiro Chinopinda, zvikurukuru mune cerebrospinal fluid iri kusimbiswa zvakafanana mune plasma revarombo. About kota uwandu anwa zvinhu yabudiswa muna weti kuchinja, vanenge 10% ukasunungurwa muchimiro metabolites, mugove zvikuru duku rokuti chinosiya muviri ari faeces.

Zvairatidza kuti zvinodhaka "TSifran" mirayiridzo kushandiswa anoreva zvakasiyana kurapwa kwezvirwere zvakawanda zvinotapukira kwendangariro. Pakati chaizvo pathologies, nokuti mishonga zvinodhaka pasi kukurukurwa iro rinoshandiswa, zvinotevera zvirwere:

• chisingaperi osteomyelitis ;

• intra-chirwere anogumbura pezvakaitwa;

• amoebic manyoka nemanyoka yakavhenganiswa mhando (amoebic uye kwemabhakitiriya);

• periodontitis, periostitis nezvimwe zvirwere zviri nomumukanwa mhango;

• gynecological anogumbura zvokurwara;

• chisingaperi sinusitis;

• Zvirwere ganda uye akapfava munyama;

• postoperative zvirwere;

• ment pute.

Mumwe wavo, uye zvimwe zvirwere zvinokonzerwa Kurovedza uye anaerobic utachiona inonyatsoziva zviito zvinodhaka zvinoriumba.

Akagamuchira kugadzirira "TSifran" postprandial. Mahwendefa zvinofanira kutorwa nemvura yakakwana akawanda. varwere Adult achitora mushonga kaviri pazuva chinyorero 500 / 600mg kana maviri 250 / 300mg. Varwere pasi pemakore gumi nemasere okuberekwa, mushonga hauna chinotarisirwa. Hazvina varumbidzwa dzokushandisa pamuviri.

Contraindications kuti kushandiswa vanorondedzerwa zvinodhaka iri kurapa ndiyo rakawedzera aikanganiswa zvakamisa hurongwa dzichiumbwa chikamu tsifran uye zvokurwara ropa, porphyria.