"Indapamide": dzomuzana. "Indapamide": wongororo vanachiremba

Ndechipi chinodhaka "Indapamide"? Analogs ari mudziyo, ayo richitungamirira, kurutivi migumisiro uye zvairatidza kuti kushandiswa zvichakurukurwa pazasi. Uyezve, munyaya ino uchadzidza kana kwete ichi zvinodhaka contraindications, zvokuita nyaya ovhadhozi sezvo kuva, kana zvichibvira chokubatanidza nevamwe zvinodhaka, uye zvavanofunga pamusoro nyanzvi pazvo.

The Kuronga zvinodhaka uye ayo kusunungurwa chimiro

Wakadiniko mushonga ichi ruripo kutengeswa? Chemishonga inogona kuwanikwa chete muchimiro biconvex mahwendefa zvemapuranga pamwe chena firimu unhani.

Ndechipi kushingaira chirungiso rinosanganisira medicament "Indapamide"? Analogs kuti mumiririri uyu (vazhinji vavo) uye kugadzirira pachayo ine vanoshingaira zvinoriumba akadai indapamide. Panyaya upiyona zvinhu, mahwendefa zvinosanganisira zvinotevera zvinoriumba: lactose monohydrate, crospovidone, povidone K-30, magnesium stearate, talc uye yavaibvisa lauryl sulfate.

The pharmacological zviito zvinodhaka

Zvakaita nzvimbo yacho zvinodhaka "Indapamide", mutengo uko kunoratidzwa panoperera nyaya? mishonga iyi ndowenyika antihypertensive pomutumwa. Mune mamwe manzwi, ndiko diuretic uye vasodilator.

Maererano zvavo pharmacological ehupfumi, mushonga ari pedyo chaizvo kune thiazide diuretics uye akagamuchira zvaipesana reabsorption pamusoro yavaibvisa munyu, izvo dziri mune cortical chidimbu kubva loop pakati Henle. It anogona kuwedzera Kushanduka kuiisa chlorine, magnesium ions, yavaibvisa uye potassium iri weti.

Sei mishonga "Indapamide"? Analogs ari mudziyo pacharo akati medicament anokwanisa ichivharira "nokunonoka" karusiyamu gwara nenzira zvokusarudza, kuwedzera elasticity mudziyo masvingo uye kuderedza zvachose vascular nemishonga (peripheral).

Kugamuchira zvinodhaka akazoita hypertrophy mwoyo, kana pane ventricle wayo kuruboshwe. Harina zvainoita huwandu lipids muropa, uyewo carbohydrate muviri, kusanganisira vanhu nezvirwere zvakadai sechirwere cheshuga.

Akati medicament akazoita aikanganiswa ari vascular rusvingo angiotensin II uye norepinephrine, yakatsiga uye kunoderedza kugadzirwa reokisijeni vakasununguka radicals, zvinoita kwetunhu prostaglandin E2.

Mushure kushandisa zvinodhaka hypotensive chiito hwapedyo pakazopera wa1 vhiki yokurapa. In ichi zvakafamba inochengeterwa kwemaawa 25 (pashure chete dzinogamuchidzanwa)

Pharmacokinetics zvinodhaka

Kunyura kupi mushonga "Indapamide"? Instructions, mhinduro kubva nyanzvi dzinoti pashure kutora mushonga mukati zvachose uye pakarepo anenge woga kubva nemudumbu. Sezvo vemishonga kuramba ayo bioavailability ndiyo 93%. Mawa kugamuchira zvokudya DZEMUNHU DZINODZORA ari Absorção de Água mwero zvishoma, asi asingaiti kukanganisa Vhoriyamu dose woga ndiye chinhu ano.

The kunonyanyisa Kuwanda basa pazvokudya plasma kunoitwa pashure anenge 2 maawa pashure kwokubatsira mumwe piritsi. The hafu upenyu zvinodhaka ndiko maawa 14-25. Communication neropa mapuroteni - vanenge 79%.

gadziriro iyi zvakanaka ichipfuura ropa-zvinyama chipingamupinyi (kusanganisira placental). Naiyewo opinda zamu mukaka.

The muviri zvinodhaka ari chiropa. Zvinonzi vaziva itsvo (sezvo metabolites) mune imwe mari 60-80%, uye 20% - kubudikidza muura.

Zvairatidza kuti kushandiswa medicament

Mune zvimwe zviitiko, varwere vari ushandiswe mushonga "Indapamide"? Zvairatidza kuti kushandisa nzira iyi vanosanganisira mumwe chete pathological ezvinhu omurwere. It neBP. Uyezve, zviri medicament vangaendeswa pamwe yavaibvisa uye mvura chengetedzo mumuviri. Kazhinji, izvi ezvinhu unogarooneka varwere chirwere chemwoyo.

Contraindications kuti kushandisa zvinodhaka

Zvino kuti munoziva zvinorehwa zvinodhaka "Indapamide" (zvairatidza kuti kushandisa mari dzave vakaisawo chete pamusoro). Zvisinei, zvinofanira kucherechedzwa kuti zvinodhaka ichi pane contraindications. Izvi zvinosanganisira zvinhu zvinotevera:

• lactose chinonyanyisa murwere;
• panguva pamuviri;
• galactosemia;
• hypokalemia;
• chirwere zvirwere kubvisa galactose kana shuga;
• lactation;
• mawa kushanda mishonga, izvo vanokwanisa kuwedzera penguva QT;
• zvakakomba renal kukundikana (kana anuria danho);
• zera munhu pasi pemakore 18 (kuchengeteka uye efficacy pakurapa vana vasina dzatangwa);
• zvakakomba hepatic, kusanganisira encephalopathy, kukundikana;
• hypersensitivity kune zvinodhaka nezvimwe sulfonamide nomukaka.

Kunyatsoverenga kushandiswa medicament

Vanhu vazhinji vanoshamisika kana kutenga "Indapamide" vanoda mushonga zvinodhaka? Kutaura zvazviri, asati kushandisa chero mushonga inokurudzirwa kuti chiremba - nyanzvi chete pashure rokuongorora uye nokuda pakuongororwa vanogona kuvaka nomazvo kurapwa zvaiitwa. Panyaya mhosva yedu, tinoona kuti vaiona chishandiso nokungwarira hwakanyanya ushandiswe kuvanhu vane chirwere cheshuga, gout, uyewo varwere vaya pane chisimbwa kuti sulfonamide nomukaka.

Mukuwedzera, mushonga zvinofanira kutorwa nokungwarira kusagadzikana pechiropa, itsvo uye mvura-electrolyte kusaenzana.

Panguva mushonga chiremba anofanira kuramba kuongorora pachiyero electrolytes muropa murwere (potassium, yavaibvisa, karusiyamu).

Drug "Indapamide": mirayiridzo kushandiswa, chaizvo nyanzvi

Maererano zvakabatanidzwa mirayiridzo, mushonga unofanira kutorwa nemuromo zvisinei zvokudya yaunodya. Hwendefa inofanira kubatwa munhu zvakakwana yakawanda mvura yakachena.

Sei kutora "Indapamide"? Maererano nezvokurara, mushonga uyu wefodya nani kubva nemudumbu chete mangwanani. Saka, Zvinokurudzirwa kuti atore chete panguva ino nhasi.

Chipimo chemushonga iri 2.5 MG (i.e., mumwe piritsi) daily. Kana pashure pemavhiki 4-8 yokurapa, zvinozoita haina asvika, bhuku mishonga haisi zvakakodzera kuwedzera (kunyange vanachiremba kuita izvozvo). Izvi imhaka yokuti pane mukuru mishonga kunowedzera ngozi yokubatwa nemishonga. Asi, zvinodhaka kurapa zvinokosha mimwe antihypertensive mumiririri kuti hausi diuretic.

Sei kutora "Indapamide" iyi? Kana concomitant kwokubatsira zvinodhaka vaviri runoonekwa nesu zvinodhaka dose anoramba kuzochinja, i.e. 2,5 MG pazuva (mangwanani mangwanani).

Zviitiko ovhadhozi: Zviratidzo, Treatment

Chii chinoitika kana ukawana vazhinji "Indapamide" chinodhaka? Reviews vanachiremba vanoti kuti muzviitiko zvakadaro murwere ane kuda kurutsa, simba uye kurutsa. Mukuwedzera, murwere mvura nokushushikana uye electrolyte mwero uye basa zvomudumbu turakiti. Mune zvimwe zviitiko, murwere ane kwazvo zvinoderedza BP uye kufema mwoyo. In varwere cirrhosis chiropa zvinogona hepatic pakoma.

How kurapa? Kana zvikashandiswa zvakapfurikidza, varwere vanofanira kugeza mudumbu, kugadzirisa mvura uye electrolyte mwero, uye kushandisa symptomatic kurapa.

Nemigumisiro pashure pakugamuchira medicament

nenjodzi pashure pokutora "Indapamide" chinodhaka aigona kuva? Side kunoita zvinodhaka izvi. Pano vari ikozvino.

• Zvomudumbu hurongwa: gastralgia, kuda kurutsa, abdominal marwadzo, kurutsa, zvinetso zvokudya, kupatira, muromo yakaoma, pfungwa nomuviri zvemwana asati, manyoka, hepatic encephalopathy.
• Respiratoria hurongwa: sinusitis, chikosoro, rhinitis uye pharyngitis.
• Tsinga: kushaya hope, kurukutika, tsandanyama chinyamunhari chinorwadza, kutya, utera, kufunganya, kutemwa nomusoro, kurukutika, vertigo, dzungu, kuora mwoyo, hope, kushatirwa, zvakawanda zvive uye kukakavadzana.
• Urinary System: nocturia, kakawanda utachiona, uye polyuria.
• Mwoyo uye ropa midziyo: arrhythmia, orthostatic hypotension, mwoyo mwero uye ECG kuchinja (kureva, hypokalemia).
• Chisimbwa: mikoko, mapundu, kuvaviwa uye Hemorrhagic vasculitis.
• hemopoietic hurongwa: thrombocytopenia, hemolytic kupererwa neropa, leukopenia, mwongo aplasia, uye agranulocytosis.
• Laboratory zvakabudiswa: glycosuria, hyperuricemia, vakawedzera urea senitrogen muropa plasma, hyperglycemia, hypercreatininemia, hypokalemia, hypercalcemia, hyponatremia uye hyposalemia.
• Other: exacerbation kuti chinonzi systemic lupus erythematosus.

Kudyidzana nevamwe zvinodhaka

Drug "Indapamide", ane chimwe nechinangwa achideredza kumanikidzwa, haisi varumbidzwa kutora, sezvo kunowedzera mukana wokuti digitalis kudhaka pachiimbwa cardiac glycosides. Kana uchishandisa izvi mudziyo pamwe karusiyamu kugadzirira uye metformin, murwere anogona kuva hypercalcemia uye zvinowedzerwa lactic acidosis.

Mawa kwokubatsira ari medicament pamwe corticosteroids, NSAIDs, sympathomimetics uye tetrakozaktidom kwakaderedza hypotensive mugumisiro aimbova. Panyaya achishandisa "baclofen", iye, nekusiyana, vakaisimbisa.

Tikafunga zvinodhaka pamwe potassium-kukudzivirirai diuretics zvinobudirira vashoma varwere. Zvisinei, izvozvo hazvirevi ushe kubva mukana hyper- kana hypokalemia, kunyanya varwere renal insufficiency uye chirwere cheshuga.

ACE FIs anogona kuwedzera ngozi hypotension uye rikwanise renal kukundikana.

Zvinogona kuvhiringa itsvo vachishandisa iodinated yomuchipatara pamatunhu mishonga.

Neuroleptics uye antidepressants imipraminovye dzinobatsira vawedzere hypotensive chiito uye mikana yakawanda orthostatic hypotension.

Mirayiridzo Special kushandiswa "Indapamide" chinodhaka

In chii Muzviitiko vanofanira kuongorora murwere ropa mufananidzo pashure kugadzwa "Indapamide" chinodhaka? Reviews vanachiremba vanoti mushonga uyu kungachinja uwandu creatinine uye potassium ions idzodzo varwere vanotora laxatives, cardiac glycosides, uyewo vanhu vakuru makore 60.

Kana kushandisa mumiririri uyu inokurudzirwa unyanzvi zvakanyatsorongwa kuongorora wevasungwa pamusoro yavaibvisa ions, potassium uye magnesium muropa plasma, sezvo varwere vanogona kuva electrolyte vachivavhiringidza. Zvinokoshawo kuti kuongorora ph, wevasungwa pamusoro uric acid, shuga, uye residual senitrogen.

Special kuzvidzora chinofanira pasi varwere chiropa cirrhosis (pamwe simba edema kana ascites), uyewo mwoyo nokukundikana uye ischemic mwoyo chirwere.

boka High-ngozi zvinosanganisira varwere yakawedzerwa QT penguva pamusoro unonzi, electrocardiograph (kungava vachiberekwa kana kutanga pamusoro pakanyorwa upi zvokurwara).

Nokuyerwa potassium Ion wevasungwa muropa murwere rokutanga inokurudzirwa kuti vhiki yokutanga pakurapwa.

Special nzeve inokurudzirwa kuti apiwe varwere cheshuga. Zvikurukuru, zvinokosha kuongorora padanho shuga muropa, kunyanya kana munhu chirwere hypokalemia.

Varwere kutora mushonga uyu, unofanira aripire kurasikirwa mvura nokudya zvinwiwa zvakawanda pazuva. Uyezve, pakutanga yokurapa, zvakafanira kuti akuteerere itsvo ushande.

Hatigoni kutaura kuti zvinodhaka "Indapamide", analogues zvakatuswa pasi apa, unogona kupa zvakanaka mugumisiro panguva doping kuzvidzora.

Varwere hyponatremia, uye BP, nokuti 3 mazuva asati pakushandisa angiotensin rokutendeutsa enzayemu FIs, diuretics zvinofanira vakarega. Treatment inogona ndokutangazve papera.

In agadza zvinodhaka "Indapamide" nyanzvi vanofanira kuziva kuti sulfonamide rinobva anogona sembura zvirwere zvakadai chinonzi systemic lupus erythematosus nyore.

Pari, vakachengeteka uye efficacy zvinodhaka pakurapa vana uye kuyaruka haana dzatangwa.

Mune zvimwe zviitiko, zvinoita munhu siyana dzinoitwa kuchinja BP. Kazhinji, izvi zvinoitika pakutanga yokurapa, uyewo kushandisa zvimwe zvinodhaka antihypertensive. Somugumisiro, ichi inogona kuderera kukwanisa kudzora muchina uye kushanda pamwe nedzimwe nzira kuti zvinoda vainyatsotarisirwa.

Anodzokorora nyanzvi uye varwere pamusoro mishonga

Zvino munoziva kuti ndiyo mushonga "Indapamide". Reviews, mutengo zvinodhaka zvichakurukurwa zvino.

Nyanzvi vanoti mushonga kuzvigona zvakanaka basa. Izvi zvinobudirira lowers BP, uye anoita somunhu diuretic.

Reviews kugadzirira "Indapamide" anoratidza kuti pashure kushanda rworuboshwe ventricular hypertrophy ipfupi, uye ayo antihypertensive kushanda hunooneka kunyange avo varwere vari pasi hemodialysis.

Kana akaipa nemashoko akati zvinoreva, kakawanda vari chokuita nechitarisiko vakawanda nenjodzi. Zvisinei, zvinofanira kucherechedzwa kuti vakadaro Migumisiro vari kuchengetwa chete nevaya vakapfuura basa chipimo chemushonga kurapwa kana kuitora, pasinei huripo contraindications.

Price uye analogues zvinodhaka

How kuzhinji chinodhaka "Indapamide"? Mutengo zvinodhaka anogona siyana (zvichienderana mugadziri uye chemishonga cheni varikumahombekombe). Zvisinei, paavhareji chokushandisa ichi inogona kutengwa nokuda 95-100 rubles Russian (Mahwendefa 30).

Asi zvokuita kana murwere asingagoni kuwana mushonga "Indapamide"? Analogues, mutengo riri asina mukuru chaizvo, inotengeswa anenge ose chezvinodhaka. Mishonga iyi zvinosanganisira zvinotevera: "indapamide kutadzisa," "Akripamid", "indapamide-din email", "CP Indamed", "Akripamid kutadzisa", "Ravel CP", "Akuter-Sanovel", "Retapres", "Arindap "" Lorvas "," Arifon "," Pamid "," Arifon kutadzisa "," Tenzar "," Ipres Long "," Vero indapamide, "" Indipam "," Indap "," Indiur "," indapamide-Verte "" Ionic "," indapamide kutadzisa-din email "," Indapres "," indapamide Sandoz, "" Ionic kutadzisa "," indapamide-OBL "," indapamide Stada "uye zvichingodaro.

Tora mari panguva yayo kungwara uye kuti kutsiva mushonga wavo "Indapamide" iri zvachose wairambidza. Vanofanira kuiganhura chete chiremba, uye chete mushure kuongorora zvokurapa. Uyewo, asati kutora mishonga izvi zvinofanira kuziva zvakabatanidzwa nemirayiridzo.

Storage zvemupiro kugadzirira uye ichiri kushanda

Drug chitoro panzvimbo yakaoma uye rima panzvimbo, ndiko dzisingambosvikiki vana vaduku. gadziriro okuchengetera tembiricha haafaniri kupfuudza 25 inegumi. The pasherefu upenyu 3 years. Shure iyi, kutora medicament iri zvaisambobvumirwa.